Drug Standards
Apexbio Technology LLC Plerixafor (AMD3100), 50mg. Cas: 110078-46-1 MFCD: MFCD05662218. CXCR4 chemokine receptor antagonist
Plerixafor (AMD3100) is a small-molecule antagonist of CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM, respectively. CXCR4 and SDF-1 are key factors in regulating cancer cell invasion and metastasis, and plerixafor can prevent the binding of SDF-1 to CXCR4 for inhibiting cancer metastasis. Plerixafor interfered with CXCL12/CXCR4 mediated retention of hematopoietic stem cells in the bone marrow, and resulted in their mobilization to the blood. Plerixafor amplified the release of circulating neutrophils from the oriented area in the lung, while simultaneously preventing neutrophil returned to the bone marrow. Three adults with WHIM syndrome were subcutaneously injected 0.01 to 0.02 mg/kg plerixafor twice daily for 6 months, circulating leukocytes were constantly increased, and associated with fewer infections. Other sizes are available. Please inqury us for quote.
U.S. Pharmacopeia Ropivacaine hydrochloride, 132112-35-7, MFCD00946578, 200 mg
Empirical Formula (Hill Notation): C17H26N2O · HCl · H2O, Molecular Weight: 328.88, Synonym: (S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride monohydrate, (2S)-N-(2,6-dimethylphenyl)-1-propyl-2-piperidinecarboxamide hydrochloride monohydrate, Naropin hydrochloride monohydrate, Ropivacaine hydrochloride monohydrate.
Med Vet International Dynarex Suction Connection Tubing w/Male Connector, Non-Conductive, 3/16" x 6' Tube, 50/Case
Dynarex Resp-O2™ Suction Connecting Tubing is designed to provide secure connections to both portable and in-wall suction sources. This non-conductive Tubing features female connectors on both ends and includes an optional male (straw) adapter for additional attachments. Designed to connect suction sources to suction catheters and yankauers Constructed from transparent material for clear visualization during suctioning Durable, crush-resistant tubing Single-use and disposable Not made with natural rubber latex or DEHP
Chem-Impex International, Inc. Protamine sulfate salt Salmon | 53597-25-4 | MFCD00132091 | 1G
Protamine sulfate salt Salmon, 53597-25-4, MFCD00132091, 1G
Medchemexpress LLC Osimertinib | 1421373-65-0 | MFCD27988062 | 99.7% | 499.61 g/mol | C28H33N7O2 | 10 MG
Osimertinib (Standard) is an analytical reference standard intended for research and analytical applications. The standard is supplied at high purity and is commonly used for qualitative, quantitative, and method development work in HPLC, GC, and MS.
- High purity suitable for analytical use (99.69%).
- Intended for qualitative, quantitative, and methodological research.
- Suitable for HPLC, GC, and MS method development and validation.
- Available in multiple package sizes, including small reference quantities such as 10 mg.
- Supplied with supporting documentation, including COA and SDS for traceability.
Med Vet International Dynarex Yankauer Suction Handle, Bulb Tip, Non-Vented, w/Pre-Attached 3/16" x 10' Suction, 20/Case
The Dynarex Resp-02™ Yankauer Suction Handle is designed to safely and effectively remove particulates and fluids from patients’ airways. The curved, one-piece Handle is constructed from transparent materials for clear visualization and features a slip-resistant, ribbed design to ensure a secure connection to suction tubing. Designed to clear airways to help improve ventilation and oxygenation Constructed from shatter-resistant plastic materials Available in vented, non-vented, bulb-tip, and straight-tip designs Sterile, single-use, and disposable for optimal hygiene Not made with natural rubber latex or DEHP
AdipoGen Streptozotocin,Chemical. CAS: 18883-66-4
Streptozotocin, AdipoGen Life Sciences. Chemical. CAS: 18883-66-4. Formula: C8H15N3O7. MW: 265.2. Antibiotic. Diabetogenic. Diabetes inducer. Induces diabetes mellitus in animal models through its toxic effects on pancreatic beta-cells. Mutagenic. Potent alkylating agent. Potent DNA methylating agent. Nitric oxide (NO) donor. Vasorelaxant. Cytotoxic to cells that express GLUT2 glucose transporter. O-GlcNAc-selective N-acetyl-beta-D-glucosaminidase (O-GlcNAcase) inhibitor. Genotoxic. Induces DNA damage. Produces DNA strand breaks. Cell death inducer. Antineoplastic. Anti-cancer agent used in chemotherapy. Induces cell cylce arrest at G2.
Selleck Chemical LLC Pirfenidone 10mg 53179-13-8 S-7701,AMR-69
Pirfenidone (S-7701, AMR-69) is an inhibitor for TGF-? production and TGF-? stimulated collagen production, reduces production of TNF-? and IL-1?, and also has anti-fibrotic and anti-inflammatory properties. Pirfenidone attenuates chemokine (CC motif) ligand-2 (CCL2) and CCL12 production with anti-fibrotic activity. Phase 3. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC Tamibarotene 50mg 94497-51-5
Tamibarotene is a synthetic retinoic acid receptor (RAR) agonist with high specificity for RAR? and RAR? over RAR?. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC Ixazomib (MLN2238) 5mg 1072833-77-2
Ixazomib (MLN2238) inhibits the chymotrypsin-like proteolytic (?5) site of the 20S proteasome with IC50 and Ki of 3.4 nM and 0.93 nM in cell-free assays, respectively, also inhibits the caspase-like (?1) and trypsin-like (?2) proteolytic sites, with IC50 of 31 and 3500 nM. Ixazomib (MLN2238) induces autophagy. Phase 3. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC Busulfan 50mg 55-98-1
Busulfan is a cell cycle non-specific alkylating antineoplastic agent. Busulfan induces apoptosis. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
AdipoGen Carboplatin,Chemical. CAS: 41575-94-4
Carboplatin, AdipoGen Life Sciences. Chemical. CAS: 41575-94-4. Formula: C6H12N2O4Pt. MW: 371.3. Potent platinum-based antineoplastic agent. Analog of cisplatin (Prod. No. AG-CR1-3590) with reduced nephrotoxicity and higher stability. Antitumor agent. Forms inter- and intrastrand DNA adducts/crosslinks, consequently blocking DNA replication and transcription and inducing cell death. Interferes with cell division by mitosis. The damaged DNA elicits DNA repair mechanisms, which in turn activate apoptosis when repair is impossible. Apoptosis inducer. Enhances radiation-induced single-strand DNA breakage. 41575-94-4