Drug Standards
Apexbio Technology LLC (-)-epicatechin gallate 1257-08-5 10mM (in 1mL DMSO)
(-)-Epicatechin gallate (ECG) is a catechin compound abundant in green tea displaying bioactivity to modulate cell proliferation apoptosis and gene expression pathways In colon HCT-116 cells ECG induces apoptosis through activating transcription factor 3 (ATF3) regulated via activation of early growth response protein 1 (EGR-1) In these cancer cells ECG upregulates apoptotic factor NAG-1 and increases caspase-3 activity at concentrations around 150 M ECG s cytotoxic potency differs among cell types with an NR50 (midpoint cytotoxic concentration) of approximately 67 M in HSC-2 oral cancer cells while normal human fibroblast HGF-2 cells show greater resistance with an NR50 near 100 M ECG metabolites identified in rat urine include various O-methylated derivatives useful as biomarkers for metabolism studies ECG serves as a research tool for oncology mechanisms and apoptosis signaling pathways
Apexbio Technology LLC Alverine Citrate 5560-59-8 10mM (in 1mL DMSO)
Alverine citrate (CAS 5560-59-8) is a synthetic small-molecule compound employed primarily in studies of functional gastrointestinal disorders It exerts antispasmodic effects predominantly via calcium channel blockade reducing smooth muscle contraction and alleviating gastrointestinal symptoms Biomedical researchers utilize alverine citrate to examine gut motility mechanisms visceral hypersensitivity pathways and potential therapeutic approaches for gastrointestinal dysfunction
Apexbio Technology LLC Ruxolitinib phosphate 1092939-17-7 100mg
Ruxolitinib phosphate (CAS 1092939-17-7) is an orally available small molecule inhibitor selective for Janus-associated kinases (JAKs) particularly potent against JAK1 and JAK2 with IC50 values of approximately 3 nM and 5 nM respectively It displays relatively lower inhibitory activity toward JAK3 (IC50 332 nM) By blocking JAK-mediated signal transduction Ruxolitinib phosphate disrupts downstream cytokine signaling pathways involved in inflammatory and proliferative responses This compound is widely utilized in biomedical research focusing on inflammatory disorders particularly rheumatoid arthritis
Medchemexpress LLC Tenofovir Disoproxil | 201341-05-1 | 99.5% | 519.44 | 50 MG
Tenofovir Disoproxil is a nucleotide reverse transcriptase inhibitor primarily used in the treatment of HIV and chronic Hepatitis B. This product is intended for research use only and is not sold to patients, providing a valuable tool for scientific studies.
- Nucleotide reverse transcriptase inhibitor
- Aids in the treatment of HIV and chronic Hepatitis B
- High purity of 99.5%
- Provides in vitro and in vivo solubility data
- Stable in powder form for up to 3 years at -20°C
- Stable in solvent for up to 2 years at -80°C
Sigma Aldrich Fine Chemicals Biosciences Sulconazole Related Compound A United States Pharmacopeia (USP) Reference Standard | 77279-29-9 | 15MG
Sulconazole Related Compound A United States Pharmacopeia (USP) Reference Standard | Mol Wt: 476.76 | 77279-29-9 | 15MG
Medchemexpress LLC Milrinone | 78415-72-2 | 99.86% | C12H9N3O | 1 G
Milrinone is a PDE3 inhibitor, and also an inotrope and vasodilator.
- Intended for research use only
- Not for sale to patients
Medchemexpress LLC Stearyl arachidate 50mg
Stearyl arachidate is a biochemical reagent that can be used as a biological material or organic compound for life science related research
Medchemexpress LLC Rebamipide impurity 6 | 90098-08-1 | MFCD34179547 | 50mg
Rebamipide impurity 6 is an impurity of Rebamipide (HY-B0360)
Sigma Aldrich Fine Chemicals Biosciences Oseltamivir impurity C European Pharmacopoeia (EP) Reference Standard | 187227-45-8 |
Oseltamivir impurity C European Pharmacopoeia (EP) Reference Standard | Mol Wt: 284.35 | 187227-45-8 |
Sigma Aldrich Fine Chemicals Biosciences Vigabatrin impurity A European Pharmacopoeia (EP) Reference Standard | 7529-16-0 |
Vigabatrin impurity A European Pharmacopoeia (EP) Reference Standard | Mol Wt: 111.14 | 7529-16-0 |
AbaChemscene,l-Naproxen,23979-41-1,Formula:C14H14O3,M. Wt. 230.26,99.44%
CS-W019918,AbaChemscene,l-Naproxen,23979-41-1,25g,Formula:C14H14O3,M. Wt. 230.26,99.44%
Sigma Aldrich Fine Chemicals Biosciences Lindane United States Pharmacopeia (USP) Reference Standard | 58-89-9 | MFCD00135947 | 200MG
Lindane United States Pharmacopeia (USP) Reference Standard | Mol Wt: 290.83 | 58-89-9 | MFCD00135947 | 200MG
Medchemexpress LLC Loxapine | 1977-10-2 | 99.9% | 327.81 | 1 ML
Loxapine is an orally active dopamine inhibitor, 5-HT receptor antagonist, and a dibenzoxazepine anti-psychotic agent. It is intended for research use only.
- Orally active dopamine inhibitor
- 5-HT receptor antagonist
- Dibenzoxazepine anti-psychotic agent
- High purity of 99.93%
- Targets human 5-HT2, D4, D1, and D2 receptors
- Reduces IL-1β and IL-2 secretion in LPS-activated cultures
- Decreases serotonin (S2) receptor density in rat brain
- Available as a 10 mM solution in DMSO
Selleck Chemical LLC Plerixafor (AMD3100) 8HCl 10mg 155148-31-5 JM 3100 8HCl
Plerixafor (AMD3100, JM 3100) 8HCl is the hydrochloride of Plerixafor, a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM in cell-free assays, respectively. Plerixafor can be used as an anti-HIV agent. *For Research & Development use only. Product is not intended for drug, household, or human consumption.